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Block PAM.
Unlock tomorrow.

Harnessing the potential of the PAM (PI3K/AKT/mTOR) pathway to improve outcomes for those affected by cancer.

Celcuity’s Gedatolisib Combination Regimens Doubled the Likelihood of Survival without Disease Progression or Death Compared to Alpelisib plus Fulvestrant in the PIK3CA Mutant Cohort of the Pivotal Phase 3 VIKTORIA-1 Trial in Patients with HR+/HER2- Advanced Breast Cancer

Celcuity is a clinical-stage biotechnology company developing targeted therapies for multiple solid tumor indications. Our lead product candidate, gedatolisib, is a highly differentiated, potential first-in-class, pan-PI3K, mTORC1/2 inhibitor that comprehensively blockades the PAM pathway. PAM is one of the most important, and difficult to blockade, pathways involved in cancer.

Our Pipeline

Advancing a robust pipeline of targeted therapies with a focus on the PI3K/AKT/mTOR pathway – Celcuity has the potential to make a transformative difference in the treatment of breast and prostate cancers.

Our Lead Candidate

Gedatolisib potently inhibits all four Class I PI3K isoforms as well as mTORC1 and mTORC2 at low nanomolar (nM) concentrations to induce comprehensive inhibition of the PAM pathway.

Our Culture

Learn more about our mission-driven company, united by a shared commitment to bring hope to cancer patients who need it most.